Sleep and Aging


Life expectancy is on the rise worldwide. Within the US alone, it is estimated that 20% of the population will be over the age of 65 years by 2030. Normal aging results in a relentless deterioration of both sleep and wakefulness. This includes sleep fragmentation and the inability to sustain wakefulness during the active phase in humans and rodents. Impairments in both behavioral states become more pronounced in many age-dependent neurodegenerative processes. Impaired wakefulness interferes with cognitive function and quality of life for millions of older Americans. Recent data indicates that sleep disruption and disorders might themselves contribute to the acceleration of development of dementia and Alzheimer’s Disease in particular.

Given the growing aging population, understanding the mechanisms of sleep/wake disturbances caused by aging is a critical step in identifying novel therapeutic strategies to increase the quality of life for the elderly as well as stave off the progression of neurodegenerative diseases. This Research Topic will appraise/reflect the current state of research in sleep and aging in basic, translational, and clinical areas.

As such, we welcome articles from scientists carrying out research that ranges from basic molecular and mechanistic, to translational and clinical.

A standard EDITORIAL TRACKING SYSTEM is utilized for manuscript submission, review, editorial processing and tracking which can be securely accessed by the authors, reviewers and editors for monitoring and tracking the article processing. Manuscripts can be uploaded online at Editorial Tracking System ( or forwarded to the Editorial Office at

Media Contact:

Kathy Andrews
Journal Manager
Journal of Clinical & Experimental Dermatology Research